Projects

VIROINF is an EU-financed Marie Skłodowska-Curie Action (MSCA) Innovative Training Network aiming to understand (harmful) virus-host interactions by linking virology and bioinformatics.

In this consortium, we study the conservation of regulatory elements and effector mechanisms in lytic and latent cytomegalovirus infection. Results from our work can be found here:

For more information, visit the project website.


The DEEP-DV consortium studies dedicated strategies that nuclear DNA viruses use to disrupt, evade or exploit nuclear gene expression networks to set the path for a lytic, abortive or persistent infection.

DEEP-DV unites scientists with strong virological expertise and firm command of state of the art methodologies such as omics-scale interrogation techniques, RNA proteomics, single-cell technologies, and bioinformatics.

In this consortium, we study the regulation and Herpes simplex virus 1 counter-regulation of transcriptional bursting kinetics in the early type I interferon response.

For more information, visit the project website.


The Collaborative Research Centre DECIDE (DECisions in Infectious DisEases) aims to identify molecular mechanisms within the host that control the course of infectious diseases. In particular, we analyze three key decisions, which determine the clinical outcome of human infections, namely (1) the initial pathogen contact to established infection, (2) the transition to persistent infection, and (3) the initiation of systemic spread.

In this consortium, we provide support for single-cell data analysis. We will build and maintain the Infection Atlas for exploratory single-cell data analysis, data sharing and visualisation. Building on the expertise of our CRC network, we will develop and implement cutting-edge sequencing technologies and computational methods as well as sophisticated tools for spatio-temporal approaches to enable in-depth analyses of data generated in the CRC.

For more information, visit the project website.